Cosmetics

[…] irritation using an alternative to the Draize methodology. The methodology is based on that described in INVITTOX 1992 No. 47: HET-CAM Test. Chorioallantoic Membrane Vascular Assay ( CAMVA) 10/14 Day The chorioallantoic membrane (CAM) of a fertilized chicken egg serves as an analog to the human conjunctiva with remarkable structural similarities in vasculature. Varying […]

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Eye And Skin Safety

[…] irritation using an alternative to the Draize methodology. The methodology is based on that described in INVITTOX 1992 No. 47: HET-CAM Test. Chorioallantoic Membrane Vascular Assay ( CAMVA) 10/14 Day The chorioallantoic membrane (CAM) of a fertilized chicken egg serves as an analog to the human conjunctiva with remarkable structural similarities in vasculature. Varying […]

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Eye-Skin Irritation Corrosion

[…] -Guideline Proprietary Method Waste Porcine Corneas GLP Healing/Reversibility Assay Sodium Fluorescein Assessment Observe Culture through Day 21 Concurrent Controls 21 Days in Duration Rapid Results Report BCOP CAMVA Cornea •BCOP •PorCORA Conjunctiva •HET -CAM •CAMVA Ocular Irritation •EpiOcular ™EIT •Irritection ® Iris  No Alternatives  Nor In Vitro Assays THE HUMAN EYE HET […]

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MB_Wheel_of_Alternatives

[…] Buehler, LLNA 10 -Rat Limit Test Rabbit Dermal Draize Study 10 -Rat Limit Test Effects on Blood Vessel Integrity Using Chorioallantoic Membrane of Chicken Eggs HET -CAM CAMVA BCOP -EIT Irritection ® PorCORA Effects on Ex Vivo Cornea, Cornea – Like Cells, or Cornea – Like Membrane None Blood Flow and Pupillary Light Reflex […]

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MB Research Labs Capabilities List

[…] y Te s t s Eye Safety  In Vitro Eye IrritaŸon Test (EIT)  Hen’s Egg Test Chorioallantoic Membrane (HET‐CAM)  Chorioallantoic Membrane Vascular Assay ( CAMVA)  Bovine Corneal Opacity & Permeability (BCOP) Test  Porcine Corneal Opacity Reversibility Assay (PorCORA)  EpiOcular™  Ocular IrritecŸon® Skin Safety  Corrositex®  In […]

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2023 Capabilities list

[…] ® OECD 435 Hens Eggs Test ChorioAllantoic Membrane Test (HET-CAM) Invittox Protocol #47 Bovine Corneal Opacity & Permeability (BCOP) Assay OECD 437 Chorioallantoic Membrane Vascular Assay ( CAMVA) Porcine Corneal Opacity Reversibility Assay (PorCORA) IN VITRO AND ALTERNATIVE SENSITIZATION ASSAYS Local Lymph Node Assay (LLNA) Flow Cytometry Method OECD 429 Local Lymph Node Assay […]

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MB-Research-Labs-In-Vitro-Capabilites

[…] ISO Skin SensitizationSkin SensitizationSkin Sensitization mbresearch.com In Vitro Eye Irritation Test (EIT) EpiOcular™ Ocular Irritection Bovine Corneal Opacity & Permeability (BCOP) Test Chorioallantoic Membrane Vascular Assay ( CAMVA) Hen’s Egg Test Chorioallantoic Membrane (HET ‐CAM) Porcine Corneal Opacity Reversibility Assay (PorCORA) ® Local Lymph Node Assay (LLNA) Human Cell Line Activation Test (h‐CLAT) Direct […]

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