SDS Safety Data Sheet Toxicological Testing

Hazard Communication Standard: Safety Data Sheets

Hazard Communication Standard (HCS) (29 CFR 1910.1200(g))

Chemical manufacturers, distributors, or importers are required to provide Safety Data Sheets (SDS) (formerly MSDSs) for each hazardous chemical.

For over 45 years, MB Research Labs has provided quality toxicity testing services to aid our testing partners with the development of SDS information.

OSHA Hazard Communication Safety Data Sheets

Link: OSHA - Occupational Safety and Health Administration Brief

As of June 1, 2015, the HCS will require new SDSs to be in a uniform format, and include the section numbers, the headings, and associated information under the headings below:

  • Section 1, Identification includes product identifier; manufacturer or distributor name, address, phone number; emergency phone number; recommended use; restrictions on use.
  • Section 2, Hazard(s) identification includes all hazards regarding the chemical; required label elements.
  • Section 3, Composition/information on ingredients includes information on chemical ingredients; trade secret claims.
  • Section 4, First-aid measures includes important symptoms/ effects, acute, delayed; required treatment.
  • Section 5, Fire-fighting measures lists suitable extinguishing techniques, equipment; chemical hazards from fire.
  • Section 6, Accidental release measures lists emergency procedures; protective equipment; proper methods of containment and clean up.
  • Section 7, Handling and storage lists precautions for safe handling and storage, including incompatibilities.
  • Section 8, Exposure controls/personal protection lists OSHA's Permissible Exposure Limits (PELs); Threshold Limit Values (TLVs); appropriate engineering controls; personal protective equipment (PPE).
  • Section 9, Physical and chemical properties lists the chemical's characteristics.
  • Section 10, Stability and reactivity lists chemical stability and possibility of hazardous reactions.
  • Section 11, Toxicological information includes routes of exposure; related symptoms, acute and chronic effects; numerical measures of toxicity.
  • Section 12, Ecological information*
  • Section 13, Disposal considerations*
  • Section 14, Transport information*
  • Section 15, Regulatory information*
  • Section 16, Other information, includes the date of preparation or last revision.

* Note: Since other Agencies regulate this information, OSHA will not be enforcing Sections 12 through 15(29 CFR 1910.1200(g)(2)).
For more information, please see:

Section 11: Toxicological Information

MB Research Labs has standard protocols designed to meet or exceed the testing requirements needed to complete Section 11 and identifies toxicological and health effects information or indicates that such data are not available.

The required information consists of the likely routes of exposure (inhalation, ingestion, skin and eye contact). The SDS should indicate if the information is unknown. Description of the delayed, immediate, or chronic effects from short- and long-term exposure. The numerical measures of toxicity [e.g., acute toxicity estimates such as the LD50 (median lethal dose)] - the estimated amount [of a substance] expected to kill 50% of test animals in a single dose. Description of the symptoms. This description includes the symptoms associated with exposure to the chemical including symptoms from the lowest to the most severe exposure. Indication of whether the chemical is listed in the National Toxicology Program (NTP) Report on Carcinogens (latest edition) or has been found to be a potential carcinogen in the International Agency for Research on Cancer (IARC) Monographs (latest editions) or found to be a potential carcinogen by OSHA.

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