Developed as an alternative in ovo toxicity assay to the Draize Rabbit Eye Test. Similar to the HET-CAM,
the CAMVA uses the vascularized membrane of fertile chicken eggs to assess a test material's potential to cause vascular changes (hemorraghing, capillary
injection, ghost vessels).
CAMVA can be used to investigate the vascular effects such as neovascularization, angiogenesis, and anti-angiogenesis, which are of particular interest
to pharmaceutical and cosmetic product research and development.