[…] irritation using an alternative to the Draize methodology. The methodology is based on that described in INVITTOX 1992 No. 47: HET-CAM Test. Chorioallantoic Membrane Vascular Assay ( CAMVA) 10/14 Day The chorioallantoic membrane (CAM) of a fertilized chicken egg serves as an analog to the human conjunctiva with remarkable structural similarities in vasculature. Varying […]
[…] irritation using an alternative to the Draize methodology. The methodology is based on that described in INVITTOX 1992 No. 47: HET-CAM Test. Chorioallantoic Membrane Vascular Assay ( CAMVA) 10/14 Day The chorioallantoic membrane (CAM) of a fertilized chicken egg serves as an analog to the human conjunctiva with remarkable structural similarities in vasculature. Varying […]
[…] -Guideline Proprietary Method Waste Porcine Corneas GLP Healing/Reversibility Assay Sodium Fluorescein Assessment Observe Culture through Day 21 Concurrent Controls 21 Days in Duration Rapid Results Report BCOP CAMVA Cornea •BCOP •PorCORA Conjunctiva •HET -CAM •CAMVA Ocular Irritation •EpiOcular ™EIT •Irritection ® Iris No Alternatives Nor In Vitro Assays THE HUMAN EYE HET […]
[…] Buehler, LLNA 10 -Rat Limit Test Rabbit Dermal Draize Study 10 -Rat Limit Test Effects on Blood Vessel Integrity Using Chorioallantoic Membrane of Chicken Eggs HET -CAM CAMVA BCOP -EIT Irritection ® PorCORA Effects on Ex Vivo Cornea, Cornea – Like Cells, or Cornea – Like Membrane None Blood Flow and Pupillary Light Reflex […]
[…] y Te s t s Eye Safety ï·ï In Vitro Eye Irritaon Test (EIT) ï·ï Henâs Egg Test Chorioallantoic Membrane (HETâCAM) ï·ï Chorioallantoic Membrane Vascular Assay ( CAMVA) ï·ï Bovine Corneal Opacity & Permeability (BCOP) Test ï·ï Porcine Corneal Opacity Reversibility Assay (PorCORA) ï·ï EpiOcular⢠ï·ï Ocular Irritecon® Skin Safety ï·ï Corrositex® ï·ï In […]
[…] ® OECD 435 Hens Eggs Test ChorioAllantoic Membrane Test (HET-CAM) Invittox Protocol #47 Bovine Corneal Opacity & Permeability (BCOP) Assay OECD 437 Chorioallantoic Membrane Vascular Assay ( CAMVA) Porcine Corneal Opacity Reversibility Assay (PorCORA) IN VITRO AND ALTERNATIVE SENSITIZATION ASSAYS Local Lymph Node Assay (LLNA) Flow Cytometry Method OECD 429 Local Lymph Node Assay […]
