MB Research Laboratories - In Vitro Toxicology - 3-D Human Tissue Ocular Irritancy Test

In Vitro Toxicology Assays

MatTek EpiOcular^TM - In Vitro Draize Alternative Tissue Model

MatTek EpiOcular^TM is an organotypic, in vitro tissue model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium.

EpiOcular - 3-D human tissue constructed with stratified, differentiated keratinocytes.

EpiOcular^TM is currently under validation as a Draize Replacement by ECVAM but since its introduction in 1985, EpiOcular^TM has been used to determine the ocular irritancy of their products without using animals by many personal care and household product companies.

Applications: product development/efficacy, claims substantiation, safety assessment, and target organ research applications.

MB Research has extensive experience in the use of EpiOcular and in vivo ocular toxicology testing. See abstract.

MB Research Labs is a MatTek-approved contract testing laboratory for EpiDerm^TM and EpiOcular^TM product evaluations. EpiDerm and EpiOcular are trademarks of MatTek Corporation.